Thursday, June 17, 2010

Thursday June 17, 2010
Therapeutic ranges anti-Xa level for adequate anticoagulation

This is important to note that therapeutic ranges anti-Xa level are different with different anticoagulation.

Heparin: 0.3-0.7 units/mL

LMWH:

  • 0.4-1.1 units/mL for SQ q 12 hr dosing.
  • For once daily LMWH dosing, the therapeutic range is approximately 1-2 units/mL.
Prophylaxis of DVT: There is no defined target range for prophylaxis of DVT. When anti-Xa levels are measured, the values are lower 0.45.